Creatine & Cell Volumizers


If you look at the label of Kill it Reloaded and Kill It, you’ll see they both contain creatine. You’ll also see they contain other cell volumizers such as taurine. Look at Kill It Reloaded, and you’ll find glycerol and betaine. Of course, cell volumizers promote water-based pumps. Not to mention, both pre-workouts have several nitric oxide boosters. Leave it to Rich Piana to create products that produce huge, hardcore pumps!

Creatine - Time-Tested & Proven!

Everyone has heard of creatine. That means there’s some misinformation about it. Some think it’s a steroid; others think it’s dangerous. However, the truth is simple enough. It’s one of the most well-researched supplements on the market, period. It’s been around since the early 1990’s. It’s stood the test of time. It’s proven safe and effective. No doubt it impressed Rich enough to be included in his pre-workouts. If it was good enough for him, it should be good enough for every 5%er.

What Is Creatine

Creatine is a compound that’s produced from three amino acids: methionine, arginine and glycine. It’s also found in meats and fish. Here’s how it works in the body: When you consume creatine through your diet, it’s converted into phosphocreatine. Then, it’s stored in the muscles to be used during your intense, brutal training sessions.

Creatine & ATP

Phosphocreatine helps create ATP. That’s the primary cellular system of energy used by your muscles. They demand ATP for short bursts of exercise. In other words, your hardcore sets and reps! So, when you hit the weights, your muscles use ATP as energy on an ongoing basis. Hardcore sets can burn ATP faster than your muscles can use it. That’s a big reason why your muscles fatigue during your training session. The bottom line is that phosphocreatine helps replenish ATP stores. By the time you’re ready to start your next set, you’ve got the energy to keep going.

What Are Creatine Supplements Used For?

Creatine as a supplement will improve in-training endurance by supporting ATP production. By increasing your body’s ability to produce ATP, you improve exercise endurance and performance. Creatine is ideal for hardcore bodybuilding and strength trainers.

Besides that, one of its biggest benefits is cellular hydration or cell volume. This concept ties into the pump because it supports muscle cell swelling. In fact, this swelling or muscle volumizing was one of the original purposes of creatine. That means creatine is the supplement responsible for water-based pumps! 5% Nutrition pre-workouts like Kill It Reloaded combine cell volumizers and nitric oxide boosters for pumps so intense, you’d make Rich proud! (1, 2, 3)

What Else Does Creatine Do?

Creatine in a pre-workout or by itself has several additional benefits. Let’s take a look.

  • Recovery - Creatine supports recovery by improving post-workout glycogen replenishment. (4)

  • Muscle Growth - Because of its cell volumization benefits, creatine is believed to stimulate protein synthesis. (5)

  • Cognitive Function - Recent clinical research indicates that creatine may support overall cognitive health and function. (6)

Don’t Forget The Cell Volumizers!

Besides creatine, Kill It Reloaded has several cell volumizers. There’s glycerol, which is a sugar alcohol that is an intermediate in carbohydrate and fat metabolism. It has exceptional osmotic properties. Also, there’s taurine, found in both Kill It and Kill It Reloaded. Taurine is an amino sulfonic acid with cognitive benefits. It has cell volume benefits as well. There’s also betaine, which is similar to and works synergistically with creatine.
In fact, all cell volumizers and N.O. boosters work synergistically. The cell volumizers pull water into the muscles and improve hydration; the N.O. boosters increase blood flow and deliver oxygen and nutrients to the working muscles. (7, 8, 9, 10)

Why Should Creatine & Cell Volumizers Be In Your 5% Nutrition Pre-Workout?

We’ve seen some of the benefits of creatine. The fact that it's a cell volumizer is enough reason to use creatine in your 5% pre-workout. After all, everybody wants a huge pump!

5% Nutrition has several hardcore Rich Piana-inspired pre-workouts with creatine and/or cell volumizers. These include the two talked about here (Kill It and Kill It Reloaded). You’ll find Full As F*ck has glycerol. Stim-crazy 5150 has taurine. Of course, you can get 5% Nutrition’s innovative Crea-TEN and add it to any other 5% product! This is our advanced 10-creatine formula. It also has a one-of-a-kind Creatine Accelerate Blend.

Leave it to 5% Nutrition to create not just one but several of the most advanced pre-workout on the market!


  2. Graef, J. L., Smith, A. E., Kendall, K. L., Fukuda, D. H., Moon, J. R., Beck, T. W., . . . Stout, J. R. (2009, November 12). The effects of four weeks of creatine supplementation and high-intensity interval training on cardiorespiratory fitness: A randomized controlled trial. Retrieved from
  3. Balsom, P. D., Söderlund, K., Sjödin, B., & Ekblom, B. (1995, July). Skeletal muscle metabolism during short duration high-intensity exercise: Influence of creatine supplementation. Retrieved from
  4. Nelson, A. G., Arnall, D. A., Kokkonen, J., Day, R., & Evans, J. (2001). Muscle glycogen supercompensation is enhanced by prior creatine supplementation. Medicine and science in sports and exercise, 33(7), 1096–1100.
  5. Ingwall, J. S., Weiner, C. D., Morales, M. F., Davis, E., & Stockdale, F. E. (1974). Specificity of creatine in the control of muscle protein synthesis. The Journal of cell biology, 62(1), 145–151.
  6. Avgerinos, K. I., Spyrou, N., Bougioukas, K. I., & Kapogiannis, D. (2018). Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials. Experimental gerontology, 108, 166–173.
  7. van Rosendal SP, Osborne MA, Fassett RG, Coombes JS. Guidelines for glycerol use in hyperhydration and rehydration associated with exercise. Sports Med. 2010;40(2):113-129. doi:10.2165/11530760-000000000-00000.
  8. Zhang, M., Izumi, I., Kagamimori, S., Sokejima, S., Yamagami, T., Liu, Z., & Qi, B. (2004). Role of taurine supplementation to prevent exercise-induced oxidative stress in healthy young men. Amino acids, 26(2), 203-207;
  10. Nitric Oxide Supplements — Research on Benefits, Side Effects, and Interactions |
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